Mystique is stronger, faster, more durable and has way now experiance, considering how much older she is. She has been confirmed on captain america and black widow level when it comes to H2H combat. She is too much for Natasha.
As good as Mystique is, Orphan is better. Even with the element of surprise, Mystique is just outclassed by Orphan. Orphan's sheer skill would catch Mystique off guard, and that would be enough to take Mystique off her game and allow Orphan to beat her.
Batman wins. Hands down. He's a much more experienced fighter than Black Widow. They're both stealth type fighters, but Batman has mastered many more styles than she has and his entire career is basically about fighting people.
She also possesses superhuman strength, speed, agility, reflexes, as well as the power of flight. And, in the movie, she defeated Ares, the Greek god of war, by channeling lightning. There would be no true contest between the Black Widow and Wonder Woman.
Heroes Reborn has altered reality within the Marvel Universe, but one thing that remains unchanged is Black Widow's fighting prowess. In fact, Natasha Romanoff just proved her incredible skills by accomplishing a nearly impossible feat: taking down an opponent with the powers of DC's Flash.
Hurting the Hulk would be hard for the Flash, especially since every missed attack would make the Hulk angrier. However, the Flash can always deploy the infinite mass punch, his most devastating attack. It would be a last resort but it would give the Flash the win.
In addition, she's sparred with Ollie plenty of times. So, it shouldn't be a surprise that Green Arrow could beat Black Widow. Granted, it would be quite the smackdown between the two but Ollie would come out at the victor.
Even with her fighting knowledge, Hulk's raw power alone is likely far too much for her to handle. Furthermore, Hulk only grows stronger as his rage increases. In a prolonged fight with Wonder Woman, he is very likely to grow ever stronger, eventually being able to completely overpower her.
A fight between them would be nasty and brutal, but Batman would win it. These two would come at each other from the shadows, hitting and running, using everything in their arsenal to take the other down, but Black Widow just doesn't have what it takes to beat Batman.
Wonder Woman is one of the toughest beings in any universe but unfortunately for her, she doesn't have the raw power to take Thanos down. She'd run through the Black Order with ease, but Thanos would be too much for her.
Natasha Romanoff was an agile, cunning, imposing, and calculated spy, which would have been more than enough to match up and even defeat Moon Knight and any of his personalities. One can only try to imagine what a fight between the two would have been like.
Weaknesses. Brainwashing: During her time as a spy for the Red Room, they mentally programmed her with certain mental commands, which can bring her under control, should she ever turn rogue. This was used by Nighthawk to put Black Widow into a comatose state.
Mystique received her first power enhancement in the X-Men Forever miniseries, in which she was exposed to dangerous levels of radiation to save the life of Toad. The process boosted her powers so that she can now morph her body into taking certain desired physical traits depending on her situation at the time.
Ultimately, Cyclops optic blasts are enough to strip Wolverine of his skin and flesh, all the way to his adamantium bones, giving Apocalypse what he needs to power his portal machine. Seeing Apocalypse mind-control Cyclops to take down Wolverine makes for quite a harrowing moment.
Wiz: There was no way that Raven couldn't read and manipulate Wanda's mind like she has to so many powerful DC Characters; some of which were considered to be gods. The Scarlet Witch may have been the Mutant Mistress of Magic, but it wasn't enough to overcome the power and varied abilities of Raven.
Non-powered humans like Black Widow and Hawkeye could compete with the Mad Titan, but in the end he's too strong. Sam has the advantage of his wings giving him an aerial dimension to the battle.
Of course, his somewhat violent tendencies works to his advantage in a fight, but the instability of his mental health would certainly leave Deadpool vulnerable to Black Widow, a formidable foe who has a lot of control over her mind and her actions.
The simple answer is Superman. It's extremely hard to see a scenario without Kryptonite where Black Widow could take Superman, even if he's without powers. A common misconception about Superman is that his only abilities come from yellow sunlight. Superman is actually highly intelligent and is extremely well trained.
By most accounts, Superman seemingly outclasses Thor in terms of raw strength, especially in earlier versions of the DC Universe. He's pulled planets, punched people into orbit, and performed all sorts of wild feats of strength.
They showcase their skills throughout the MCU in up-close fighting situations and even do so against each other at points. However, even though Hawkeye has skills in this department, Black Widow has the edge.
But even then, there's no doubt about the outcome of a fight between the two heroes: Black Widow would wipe the floor with Hawkeye. They haven't fought many times but when they have, Black Widow won.
It makes sense that despite some struggles, Captain America would've emerged the winner. The super soldier serum and the shield would give him too many advantages. Black Widow's best weapon against him is her own fighting skills, but the problem with that is that his are on a similar – if not higher – level.
