Sadly, the answer is yes; after the midnight assault on Fangtasia, when those H-Vamps exploded all over Sookie, she contracted the Hep-V virus and passed it along to Bill during their feedings.
Her “baby girl” comes first. Sookie gets tested to see if she is the one who infected her ex-boyfriend Bill with Hep-V and discovers that she was indeed infected after using herself as bait to catch the mob of infected vampires that had been terrorizing Bon Temps.
At the end, Sookie returns to Bill, determined to be with him again before he dies. Sarah is found and captured by Eric, Pam and Mr. Gus; upon drinking from her, Eric is almost instantly cured of his Hep-V.
Bill was infected by Sookie Stackhouse, and the virus seems to have mutated into an accelerated form through her blood. While faerie blood in general when infected, may mutate the virus, the blood of a faerie or halfling of a powerful bloodline causes the virus to mutate at an exceedingly accelerated rate.
The reason Eric left Bon Temps and fled to Sweden in the first place was because he was so devastated by the death of his sister (and lover) Nora. She succumbed to Hep-V in his arms — perhaps he wishes to join her by dying of the same disease.
However, in season 7, the audience finds out that Eric Northman is alive, although he has contracted the Hep-V virus. In episode 8, Eric is cured of the Hep-V virus. In the final episode there is a flash forward 4 years and Eric is still alive, running a corporation called New Blood.
After discovering that he is dying from Hepatitis V, she begs him to take the cure and live out his life with her, but Bill refuses. He wants her to have a better life, a life in the sun, children and a family, so he makes an unforgivable choice on her behalf, and asks her to kill him.
Hep V-positive Arlene even entered a sexless relationship with a vampire (surely there are condoms in Bon Temps?) and Jason, the town strumpet, ended up just snuggling Hoyt's ex-girlfriend with his undergarments intact.
No matter what Bill did to Sookie, her friends, or her family he always ended up professing his love for her. Every time he did something that didn't have the best outlook he always had a greater reason.
In the fourth season, Bill becomes the Vampire King of Louisiana after staging a coup d'état against Queen Sophie Anne with the help of the Authority. He becomes an antagonist throughout much of the fifth and sixth season after drinking the blood of Lilith (known as the Progenitor of the vampire race.)
By its finale, True Blood saw the once Southern gentleman turned wayward villainous jerk meet his "true death" when he asked Sookie to kill him. After refusing to drink the cure for his rapidly progressing Hep-V infection, Bill chose to die to free Sookie from her undying love for him.
"The idea was that we wanted Bill to be correct when he said that Sookie could have a normal life, the twist, of course, being that Sookie chose to keep her power and specialness and persevere—despite his belief that she couldn't be okay without giving up her powers," Buckner says.
At the end of True Blood, viewers were treated to a flashforward of a married—and pregnant—happy Sookie (Anna Paquin) at a Thanksgiving dinner. Her mystery man was never revealed, but he was played by stuntman Timothy Eulich. After Bill's death, Sookie went on to fulfill his wish and live a normal life.
Warlow deeply loves Sookie and mentioned that whenever he sleeps, he'd dream of Sookie and spending the rest of his life with her. Another side of Warlow was revealed when Sookie hesitated to be turned into a vampire. Warlow lost all patience and began to forcefully turn her.
In the course of the first novel, Dead Until Dark, Sookie loses her virginity to the vampire Bill. She does it outside of wedlock, without apology or regret, but she doesn't see herself as a loose woman by any means.
When Eric gets his memories back, he tells Sookie that he remembers their relationship and declares his love for her. Sookie admits that she's fallen for him, but that a part of her still loves Bill. At the end of Season 4, Sookie decides to not be with either Bill or Eric, as she loves them both too much.
After appearing to develop an affection for Sookie in the third book in the series, Club Dead, Eric has a brief romance with her in Dead to the World, the fourth book, though, due to a curse, he lost his memories of that time until From Dead to Worse, the eighth book.
Bill only breaks Sookie's heart to keep her safe from Lorena. Remember Lorena? Bill and Sookie's big breakup in season three comes when Lorena is relentlessly trying to kill Sookie. Sookie agrees to the breakup when Bill nearly kills her by draining her blood shortly thereafter.
The pair met on the set of HBO's True Blood, which aired from 2008 to 2014. Paquin and Moyer played Sookie Stackhouse and Bill Compton, respectively. While the couple got together months after filming began, they kept their relationship under wraps until February 2009.
Vampire Eric Northman (Alexander Skarsgard), who rid himself of hep V by biting Sarah's neck, tries to change Bill's mind for Sookie's sake. “What you're doing to her is unconscionable,” Eric insists.
Eric's Hep-V was cured when he and Pam (Kristin Bauer van Straten) found Sarah, with the yakuza close in pursuit. In characteristic form, they escape with Sarah while slaying the gangsters.
Almost 4 years later, after Sookie agreed to stake Bill, leaving her heartbroken, New Blood has been released to the market, and the Hep V epidemic has ended. Jason and Bridget are married with many kids. The last scene shows the family and friends of Sookie and Jason enjoying dinner at the Stackhouse.
Bill kills the uncle who had molested Sookie as a child without asking her permission; he's constantly feeding on her to save his own life; he cheats on Sookie with his Maker in the single most disturbing sex scene I have ever had the misfortune to watch; he knows that she's not fully human and never says a word; he ...
In Dead Ever After, the final book in the series, Sam and Sookie begin a romantic relationship. In the companion book, After Dead: What Came Next in The World of Sookie Stackhouse, it is revealed that Sookie and Sam get married and had four children. Sookie and Sam continued to tend Merlotte's until their retirement.
A spin-off of True Blood that follows Jessica Hamby (Deborah Ann Woll) as she discovers what it's like to be a "Baby Vamp" in the small town of Bon Temps.
