According to Marvel Database, Madame Web (née Cassandra Web) suffers from the rare neurological disease myasthenia gravis. She is blind and confined to a web-like life-support system designed by her husband.
A flashback shows that she was meant to have myasthenia gravis, but a bite from a Peruvian spider upon her pregnant mother cured her. By the movie's end, however, a climactic battle leaves her blind and paralyzed, reflecting the incarnation of Madame Web from the comics.
Does Madame Web have myasthenia gravis in the movie?
In the original story, Madame Web, a.k.a. Cassandra Webb (who is played in the movie by Dakota Johnson) has a condition called myasthenia gravis, which made her dependent on a life support system that looked like a massive spider web.
In the comics, Madame Web is actually an elderly woman who is blind and uses a wheelchair because she has this same condition. In the movie, the spider bit Cassie's mom right before she was born, cured her of the disease, and gave her the power of foresight with its venom.
MADAME WEB: How SPIDER-MAN BROKE The SPIDERVERSE Explained!
What disease does Madame Web have?
Madame Web was a victim of myasthenia gravis, a disorder of neuromuscular junction transmission. As a result, she became entirely dependent on external life support for survival. This is no longer the case as she was cured of the condition some time ago. She is also blind and relies on her powers to compensate.
How Madame Web Goes Blind And Becomes Paralyzed. During the final fight between Madame Web and Ezekiel Sims, Cassie is thrown into the water where she's hit with a blast from one of the explosions.
After a near-death experience triggered her clairvoyant powers, Webb was forced to use her new abilities to protect Julia Cornwall, Mattie Franklin and Anya Corazón from Ezekiel Sims. After saving the girls, she lost her sight and became a paraplegic.
During her final confrontation with Ezekiel Sims, Cassie finds herself knocked unconscious and plunged into a river. Under the surface, she gets hit by a piece of falling debris, which blinds her and presumably severely injures her body too.
She debuted in The Amazing Spider-Man #210, published in 1980. According to Marvel Database, Madame Web (née Cassandra Web) suffers from the rare neurological disease myasthenia gravis. She is blind and confined to a web-like life-support system designed by her husband.
Why can't Madame Web walk at the end of the movie?
Back in New York, Cassie uses her powers to save Julia, Mattie, and Anya from Ezekiel — but she essentially sacrifices herself to do it. Cassie is paralyzed by Ezekiel's neurotoxins, blinded by a neon Pespi-Cola sign, and nearly drowned in the East River.
Madame Web is a superhero movie about someone with precognitive powers: To the extent that you can actually understand what her powers are, it's that she can see the future and in some cases act to stop terrible events from happening.
If you thought “Morbius” was a flop, you're not gonna wanna watch “Madame Web.” The writing was cheesy, the timeline was hard to follow, the movie was too fast-paced and the acting was awful.
The acting is lacking, the actors look as bored as you will feel. Script is bad, just some beyond silly lines, the story chops and changes so much your neck will hurt you, some bad CGI, and just boring action.
While some fans tend to be hard on recent superhero movies, Madame Web has already received plenty of criticism. From a poor script to nonsensical plot points and unlikeable characters, Marvel fans have come up with plenty of valid reasons to dislike the new movie.
Webb finds herself having to protect three teenagers from Ezekiel Sims, a murderous adversary with superhuman powers who is hunting them. “Madame Web” is set in 2003 and sort of pays homage to the conventions of the comic book movies of that era.
Why is Cassie in a wheelchair at the end of Madame Web?
Ezekiel falls to his doom but Cassie doesn't make it out unscathed, being blinded and paralyzed as a result of the fight. In the aftermath, Cassie is seen meeting up with the youngsters and wearing sunglasses while in a high-tech wheelchair.
Thanks to her newly discovered powers of weaving — which include astral projection — Cassie saves all three of her young charges but ends up almost drowning. Thanks to an earlier impromptu CPR lesson, her life is saved by her newfound family of future Spider-Women.
Madame Web continued to assist Mattie during the rest of her time as Spider-Woman. The Spider-Women team eventually disbanded. Madame Web has since become elderly again, although she presumably has retained her immortality, potentially condemning her to an eternity in her current condition.
In Marvel comics, Madame Web is an elderly, blind woman in a wheelchair, and Sony intended to create a franchise where she leads a younger team of Spider-Women, including Euphoria's Sydney Sweeney.
In Madame Web, she's pregnant with her first child, a child that's heavily implied to be Peter. Mary never confirms her baby's name on screen, but at one point, she hints at Peter's future acrobatics, joking that the baby is really “leaping around in there.”
