Superman has 4 basic weaknesses that affect him physically. These are high gravity, a red sun, magic and Kryptonite. High gravity is a weakness for Superman it that it will cause him to lose his super strength, speed and other powers that come from Earth having a lower gravity than Krypton had.
However, Superman is still very durable, even under the effects of green Kryptonite. On the other hand, the effects of gold Kryptonite remove one's powers entirely.
Pink Kryptonite alters the sexual orientation of Superman and all other Kryptonians. While it doesn't affect the strength of Kryptonians, it changes their orientation. In the case of Superman, it turns him gay.
But kryptonite is just one of Superman's weakness. The hero is also vulnerable to red solar radiation, which robs him of his powers, as well as magic which can completely disarm the hero.
Captain Atom has proven in past battles that he is stronger than Superman and has better fighting skills. He can also weaponize red sun radiation, which can weaken Superman like Kryptonite and magic. His sometimes uncontrolled nature has earned him a reputation as one of the most dangerous DC heroes.
For most of the fight, Shazam is winning without using the full extent of his powers because of his deep respect for Superman. While Superman ultimately wins, it's only because he's able to cover Batson's mouth.
One of the most famous holdovers from the original William Moulton Marston years was the idea that Wonder Woman's weakness should be the inability to escape bonds tied by men.
Batman's lack of superhuman abilities makes him especially vulnerable to physical trauma, as his body cannot withstand continuous beatings without severe consequences. Batman's past trauma and lack of emotional healing make him easily manipulated by his enemies, who use his fears and personal losses against him.
Yes, unfortunately he can be killed without the use of magic or Kryptonite. Superman was first killed by the Kryptonian abomination named Doomsday during The Death of Superman arc.
Most people know about Superman's aversion to Kryptonite. Surprisingly, that isn't even his greatest weakness! In fact, magic circumnavigates all of his biological abilities. No matter what color of sun he's under, no matter what the situation is, magic is extremely effective against Superman.
Unfortunately, the last remaining pieces of Krypton are now deadly to Superman. Exposure to Kryptonite severely weakens the Man of Steel and causes him to lose his incredible abilities.
There's no question the Hulk is a near-indestructible force who comes out on top in almost all of his battles of pure strength. However, against Superman, he's outmatched. While Hulk's strength might rival that of the Man of Steel, Superman's other abilities give him a considerable edge against his opponent.
By most accounts, Superman seemingly outclasses Thor in terms of raw strength, especially in earlier versions of the DC Universe. He's pulled planets, punched people into orbit, and performed all sorts of wild feats of strength.
Despite being an unstoppable force, powerful beings like Namor, Wolverine, Iron Man, and Deadpool have managed to outsmart and defeat the Hulk. From fellow superheroes to average soldiers, various characters, including Hawkeye and even Batman, have successfully taken down the Hulk.
Captain America remains unwavering in his pursuit of truth, justice, and freedom, even at great personal cost. Steve Rogers' belief in doing the right thing may be his biggest weakness, leading to unforeseen consequences.
He also retroactively developed a specific weakness akin to Superman's vulnerability to kryptonite or Green Lantern's vulnerability to the color yellow: Aquaman had to come into contact with water at least once per hour or he would die. Prior to this, Aquaman could exist both in and out of water indefinitely.
Tony Stark's heart is electronically powered and can run out of battery if he uses too much power in his suits. This is one of his main weaknesses because the heart can give out during the course of a highly intense battle.
In the MCU movies. His physical weakness is blade weapons. He defended himself from Loki's knife. Set up an illusion on Knowhere, when Gamora attacked and cut his throat(and she wasn't too surprised it worked) Almost killed off-screen by Nebula (Probably with her knife)
This is the big one. Ethyl chloride is essentially Spider-Man's Kryptonite and it renders anyone's spider-powers null and void. This makes ethyl chloride extremely powerful against Spider-Man, but this chemical cocktail doesn't have nearly the same reputation as Superman's Kryptonite.
Like most Asgardians, Thor is vulnerable to particular types of magic. One type of magic of Thor finds himself particularly vulnerable to that magic meant to charm an opponent. This makes Thor vulnerable to foes like Enchantress and her younger sister Lorelei.
After decades of debate on who would win between Batman and Superman, Batman v Superman: Dawn of Justice pitted The Dark Knight against the Man of Steel — with Ben Affleck's aggressive version of Batman coming out victorious.
Steve Rogers is one of the few mortals able to not only lift Mjolnir, but wield its full power, making him someone who legitimately could defeat Thor. Assuming the reason for their battle is due to Thor being deceived, possessed, or otherwise out of his mind, Cap would be able to use Mjolnir against him.
