A key advantage that Hulk has over Saitama is his ability to heal/regenerate himself. Hulk has one of the strongest healing factors in all of Marvel, rivaling even Wolverine's ability to heal. This is not a power that Saitama is ever shown to have.
The battle between Saitama and Thanos was intense and destructive, but ultimately, Saitama's immense strength and speed proved to be too much for even the all-powerful Thanos with all six Infinity Stones.
However, there are several anime characters who can easily defeat him, like Gremmy, Altair, and Saiki, who possess unique and overpowering abilities. Characters like Lain, Accelerator, Heaven Ascension Dio, Anos, and Rimuru have powers that can manipulate reality and destroy Saitama effortlessly.
Between his ever-increasing strength, durability, and healing factor, Hulk has what it takes to survive Goku's most powerful assaults. Goku could stay out of Hulk's way for a while, but once he gets within the Hulk's grabbing range, the fight is over.
Will he able to destroy it with One Punch? He would find he can't lift it. At best Saitama has demonstrated planetary levels of strength with ease. However, Mjolnir is not something you can lift via strength.
Thanos and Hulk have clashed several times in Marvel lore, with Thanos even admitting he was scared to face the Hulk before acquiring the Infinity Stones. While Thanos is usually the victor, it's generally down to him using superior tactics and technology, rather than simply possessing greater physical strength.
As a Saiyan, Broly can fly, teleport, move at super speed, and emit powerful blasts of energy, whereas Hulk's primary power is his strength. His healing factor gives him an edge, but other Marvel characters have beaten Hulk in the past, meaning Broly could feasibly overpower him as well.
No, it's not that simple. A true omnipotent, by definition, has all strength and no weakness. There is no strength lacking in that being. Therefore, Saitama beating God doesn't mean Saitama can defeat omnipotence... it just means God wasn't actually omnipotent since he lost.
Saitama's unmatched strength surpasses logic and common sense, making the Goku vs. Saitama debate nearly pointless. Saitama's vast powers extend to durability, speed, and unique abilities, putting him above countless anime heroes.
It's been shown many times that a wizard can dodge spells. So Saitama would have no trouble remaining untouchable in their fight as he is even faster than Speed-o'-Sound Sonic. If he can jump off the moon and land back on earth in a couple seconds, he would have no trouble winning.
On the other hand, Saitama does not possess potential like Superman does. Instead, he possesses limitless powers, enabling him to lift anything, regardless of its infinite weight. Saitama's character is designed to mock and surpass all other powerful characters in fiction, serving as the epitome of strength.
Given this premise, in a straightforward one-on-one physical battle, Saitama, aka One-Punch Man, would likely emerge as the victor, as his power is portrayed as limitless and invincible.
It was one of the more epic Marvel events in recent memory. And with this issue showing that Hulk, when mad enough, can take down an actual god, it's no wonder that MCU Loki was so scared when he saw the not-so-jolly- green giant show up in Ragnarok.
His adamantium claws are one of the few weapons in the Marvel Universe that can consistently pierce Hulk's skin and Wolverine has no problem going for Hulk's head. In fact, if it came down to it, Wolverine could cut Hulk's head off, ending the Hulk once and for all.
The simple answer is no. Yes, Hulk absolutely smashes Thor to the ground with Mjolnir, but, he's holding both Thor and the hammer. Hulk wouldn't have been able to lift Mjolnir by himself, but since the God of Thunder had a firm grip on it as well, he was able to use it as a weapon against his teammate.
There's no question the Hulk is a near-indestructible force who comes out on top in almost all of his battles of pure strength. However, against Superman, he's outmatched. While Hulk's strength might rival that of the Man of Steel, Superman's other abilities give him a considerable edge against his opponent.
Putting it all together, Thor can win against the Hulk, even if he can't kill the Jade Giant. Hulk is practically immortal and has unlimited reserves of strength and stamina, so he can keep fighting forever. Thor's endurance, while godly, is not limitless, so he will eventually lose a prolonged battle.
Saitama can literally destroy the world with one punch if he wanted to, but he doesn't because he only wants to be a hero and play video games like everyone else.
