However, certain weaknesses can be utilized to kill Deadpool. A fairly unknown fact about Deadpool is that he is weak when in contact with heavy Gamma radiation. Prolonged exposure to Gamma radiation significantly reduces Deadpool's regenerative abilities, making him easier to take down.
A little-known fact about Deadpool is that he doesn't do so well with Gamma Radiation. Deadpool's healing factor is among the most powerful in Marvel, but if the Merc with The Mouth is exposed to excessive Gamma Radiation, his healing factor is all but gone.
Readers witnessed Wade Wilson's rapid regeneration abilities and Rogue's absorption powers work together at an unbelievable level, saving Rogue's life – and proving Deadpool can survive a nuclear blast.
His power is so effective that it allows him to be immortal despite him carrying his cancer. But that doesn't mean he is unkillable. One way of killing him is to put a mutation-dampening collar on his neck. It will disable his regenerative ability and allow the cancer cells to grow, thus deteriorating his body.
Likewise, an unexpected dip in lava during Deadpool's stint on the Thunderbolts seemed to destroyed him in Thunderbolts #26 by Charles Soule and Paco Diaz Luque, destroying his body completely and preventing him from healing from even a single cell -- only for Thunderbolt Ross to reverse the event by changing the past ...
In the pages of Marvel Comics, Wolverine's healing factor has helped him survive impossible situations, from being ripped apart from Magneto, getting torn in half by the Hulk, and taking on a nuclear bomb head-on and making it out alive.
Most likely, Deadpool would have to place his head back onto his neck, and it will then Regenerate in that location. This is also seen possible because of this, yes I know this is just epic cover art to build suspense, but it shows us that Deadpool can actively hold his head rather than it just regenerating instantly.
In the end, Deadpool wasn't worthy. While he seemingly had control of Mjolnir and the strength of Thor, it was all a mirage put on by Loki to distract Thor.
There's not really much one can do when facing an opponent whose prime ability is to never perish. Hence, Thanos would have no chance against Deadpool if he was facing him without the Infinity Gauntlet. Thanos can eradicate entire civilizations and wipe out half of all life in the universe with a snap of his fingers.
While the Hulk was easily able to survive the barrage of nuclear weapons, the noise of the explosions and cries of dying people eventually came to bother him. The Hulk returned to his birthplace in New Mexico and sealed himself in a cave with a massive boulder, trapping Banner inside with him for many years.
Eventually, Wade gets out from under Stryfe's thumb, but the real miracle is that Deadpool survives the freezer in the first place, whether he is left insane or not.
Originally Answered: Would a nuke explosion kill Deadpool? nope, Deadpool was cursed to be immortal so that he and lady death can never be together since Thanos is in love with Lady death and she is in love with deadpool.
Deadpool is a low-power-level hero, but he can survive anything and is smart enough to devise ways to kill pretty much anyone. He used stealth, misdirection, and smart tactics to destroy everyone, including Wolverine.
Yes, Deadpool feels every bit of pain as normal humans do. However, his regenerative ability allows him to heal from all injuries. While Deadpool can heal quickly, he isn't indestructible.
Since Mjölnir can only be wielded by the worthy, Juggernaut has no chance of lifting it. However, that doesn't stop him from using it. In most fights against Thor, Thor throws his hammer at full speed towards Juggernaut, but Juggernaut's mystical force field stops Mjölnir in mid-air.
Loki is confirmed to be worthy of lifting Thor's hammer, Mjolnir, for the first time in official Marvel canon. In The Immortal Thor #5, Loki confidently catches and wields the hammer, showcasing his growth and heroism.
While most people have a hard time resisting the cuteness of kittens, Deadpool notoriously mentioned that the young furry felines are his one true weakness.
This question is answered by the fact that Deadpool's cancer hasn't actually been cured but simply put on pause, meaning it is constantly battling with his healing factor, causing his severe disfigurement, which will assumedly still be in place when Deadpool joins the MCU in Phase 5.
Deadpool's new powers as Apocalypse's Famine manifest through the antihero's mouth, from which Deadpool can conjure a deadly cloud of locusts. In order to control this ability, Deadpool has his mouth sewn shut, and only breaks the stitching when he needs to unleash his disgusting yet incredibly effective new ability.
His adamantium claws are one of the few weapons in the Marvel Universe that can consistently pierce Hulk's skin and Wolverine has no problem going for Hulk's head. In fact, if it came down to it, Wolverine could cut Hulk's head off, ending the Hulk once and for all.
(Vol. 2) #50 (by John Arcudi, Armando Gil, Gina Going, and Janice Chiang), the Hulk hit Wolverine so hard it destroyed his bones and brain inside the adamantium, killing him.
Wolverine's ability to rapidly heal from any injury is both a blessing and a curse, as he has suffered more pain and injury than any other hero. Wolverine has survived numerous traumatic experiences, including drowning, being shot with dozens of arrows, and being shot in the head with an adamantium bullet.
