Thanos from the Marvel Cinematic Universe would likely defeat Supergirl. While Supergirl possesses incredible superhuman abilities, Thanos' strength, durability, and mastery of the Infinity Stones give him an overwhelming advantage.
That villain is, of course, Kang the Conqueror, who's set to be the Avengers' next opponent in the upcoming Avengers: The Kang Dynasty. And while Thanos is certainly a hard act to follow, Kang may be a far greater threat than the Mad Titan ever was.
Hercules is known to run into battle without thinking and that's not something that works very well against Thanos. Thanos is just way too powerful that sort of thing. So, while Hercules would definitely be able to do a lot of damage quickly, his lack of planning and limited power set are going to cost him.
That's not to say no single hero can't beat him, as heroes like the original Captain Marvel, Adam Warlock, and Silver Surfer all have victories over him. DC's heroes are often more powerful than their marvelous counterparts, which would give more of them a chance to beat Thanos entirely on their own.
There's no question the Hulk is a near-indestructible force who comes out on top in almost all of his battles of pure strength. However, against Superman, he's outmatched. While Hulk's strength might rival that of the Man of Steel, Superman's other abilities give him a considerable edge against his opponent.
He has centuries of battle experience, the hones skills of a warrior, and one of the most powerful weapons in the universe. Putting it all together, Thor can win against the Hulk, even if he can't kill the Jade Giant.
He has feats such as defeating Surtur (who can destroy a planet), conquering the 9 realms, and sealing away Hela. While there isn't much doubt that Thanos could beat Odin if he had all 6 stones, Odin could probably defeat Thanos if he only had one or two of them.
On a normal day, Zeus would wreck Thanos, but he is never winning while Thanos has the Infinity Gauntlet. Thanos using it makes him the strongest being in the Marvel universe. To recap, Thanos using the Infinity Gauntlet killed half the living things in the universe with a thought.
Writers often take artistic licenses when dealing with Hercules' strength, as Stan Lee himself pointed out at one time. However, it is undeniable that Hercules has bested both Thor and Hulk, proving he is indeed the strongest Avenger.
As mighty as they are, neither Thanos nor Superman is immortal. Both have been killed in the past, meaning neither is unbeatable. However, Thanos would need an ironclad plan to trap and defeat the Man of Steel, because if it comes down to plain old fisticuffs, Superman is definitely going to win.
Few characters can stand against him, with only a few being so brave and some being very foolish. While the MCU Hulk was not able to defeat Thanos, his comic book counterparts pose a better chance to make an even fight particularly if Thanos does not wield the Infinity Gauntlet.
In addition, Thanos can consciously metabolize the power cosmic, using its limitless potential to remain invulnerable to attacks — even from characters as overpowered as Odin and Thor. Loki might be proud of his Asgardian durability, but he is to Thanos what a sheet of paper is to a brick wall.
Yes he can, he not only welded DC'S version of Mjolnir but also Marvel's Mjolnir. While later on in the story he couldn't do it, it was later retconned in Jane's Mighty Thor run that Superman is worthy.
While Thanos may be a more capable commander or general combatant, Goku is the perfect duelist and excels in one-on-one fights, arguably his best type of fight. That experience is much more relevant in a battle between the two, meaning that Goku comes out on top.
While it is fairly obvious that the Flash could run circles around Thanos under normal circumstances as his powers make him virtually untouchable, there wouldn't be much the Scarlet Speedster could do if he was around for Thanos' Infinity Snap as there is no way to outrun the god-like power of cosmic chance.
The Olympian easily defeated the Hulk and tested his healing factor in their fight. While Hulk's powers kept the hero alive, it was pushed to its limits by Zeus, who proved he was even stronger than the Jade Giant.
In a Zeus vs Thor scenario, Zeus would probably end up the victor, but the same goes for his son, Hercules. Technically speaking, he's only a demigod, but, if any biceps could outsize Thor's, then it is the Herculators.
Indirectly, Kronos already defeated Thanos by creating Eon in the Earth-9997 version of the comics (the entity teleported the Kree Captain Marvel to win against the Mad Titan). In terms of direct combat, Kronos can easily attack Thanos with infinite and lethal doses of cosmic energy attacks.
Storming the palace and sacrificing Asgardian lives, Odin stood between Hela and the throne. Unable to kill his own daughter, Odin defeated Hela and imprisoned her using his own power to keep her at bay in another realm for eons.
He doesn't fear Odin to the point even a spear-wielding All-Father respects him as an adversary worth saluting, considering him as a foe he's never fought in eons.
He transported Thor back to Asgard where Odin took this as an act of war and fought an extremely destructive battle with Thanos. Even upon learning the truth, Odin did not thank Thanos for his reluctant altruism, but told him to leave and never return.
Even so, taking both heroes at their maximum potential, it's practically a given that Superman would overpower Thor in terms of sheer physical strength. He may not consider himself a god, but the Last Son of Krypton can still outmatch the God of Thunder on his best day.
The Hulk reigns supreme over Iron Man in raw power. The embodiment of unfathomable power, his strength knows no bounds, growing exponentially as his anger intensifies.
While Hercules may have the strength to literally destroy Thor's body, Thor can technically do the exact same thing to Hercules. The Olympian and the Asgardian are evenly matched in terms of both strength and durability.
