The point of Mjolnir is that it can only be lifted if its wielder is “worthy”. In reality the hammer only weighs around 40 pounds which most adults should be capable of lifting. All in all it really depends if Saitama is worthy but if you remove the spell then Saitama could easily lift Mjolnir.
Other than Thor and Odin, certain other individuals have proven worthy of lifting Mjolnir in the primary continuity: Roger "Red" Norvell (a deliberate ruse by Odin) Beta Ray Bill. Buri (also known as Tiwaz, Thor's great-grandfather)
Summary. Saitama's strength is finally put into context in the latest chapter of the One-Punch Man manga, as he is able to lift and move an aircraft carrier, which weighs at least 100,000 tons.
Gravity is about 1/5th as strong as Earth's on Io, so with a mass of 89.3 x 10^21 kg (half of Io canceling out the one-handedness), Saitama at the time could probably effortlessly lift 16 quintillion tons on Earth.
Physical Abilities. Immeasurable Strength: Saitama possesses an immeasurable amount strength and as a result is capable of destroying powerful monsters and villains with a single one punch (though this strength is not limited to punches).
The simple answer is no. Yes, Hulk absolutely smashes Thor to the ground with Mjolnir, but, he's holding both Thor and the hammer. Hulk wouldn't have been able to lift Mjolnir by himself, but since the God of Thunder had a firm grip on it as well, he was able to use it as a weapon against his teammate.
It's important to note that the rules around worthiness had been temporarily suspended to allow this to happen. As soon as the fight was over, Superman couldn't lift the hammer anymore. However, under normal circumstances, without any weird interference, Superman is worthy of Mjolnir.
In the end, Deadpool wasn't worthy. While he seemingly had control of Mjolnir and the strength of Thor, it was all a mirage put on by Loki to distract Thor.
In a battle against Hulk, every little bit counts. Saitama having this ability provides him a slight edge, as he effectively has a source of projectile attacks that he can use at a distance.
God claims that he can't be destroyed, but Saitama destroys him and the universe with a single overwhelming punch. Fans are left to wonder where One-Punch Man is going to go now that literally nothing exists anymore.
Odin. Effortlessly. Saitama may have overpowered Boros's Collapsing Star Roaring Cannon with his Serious Punch. Which would have destroyed the surface of Earth (manga) / destroyed the entire Earth (anime).
Even if Goku was able to use his highest form of power, Saitama's one-punch certainty means a fight wouldn't last for long. If we are to take Saitama's power and accuracy at face value, it almost doesn't matter who his opponent is — he would win outright.
But after going through the Ninja War and spending years training and honing his craft, he eventually becomes worthy of becoming the Hokage. And in doing so, he's also worthy of wielding Mjolnir—because his own way of leading and caring for those around him makes him a perfect candidate.
Saitama could probably take down most of the heroes, but with powerhouses like Dr Strange or Ghost Rider who could potentially defeat him (send him to another planet or stare at him to get his guilt to kill him, though Saitama is devoid of emotion), he may have a hard time beating them all. The Avengers would win.
Surprisingly, the answer is almost certainly, “No.” Although Batman's will and moral compass do make him a worthy candidate for Thor's hammer, his track record with super powers is less than stellar. In several storylines, Batman has acquired genuine superpowers but frequently becomes corrupted by them.
While Superman could potentially overpower Thor, blows rendered by the mystical Mjolnir would likely impose serious damage on the Kryptonian hero. With his super-speed, the Man of Steel could probably avoid the Thunder God's lightning, but not necessarily, since Thor is just as fast.
After bashing Thor with an entire stone pillar, Juggernaut managed to separate Thor from his hammer – but was unable to lift it as a selfish brute like him was unworthy of its power.
Loki is confirmed to be worthy of lifting Thor's hammer, Mjolnir, for the first time in official Marvel canon. In The Immortal Thor #5, Loki confidently catches and wields the hammer, showcasing his growth and heroism.
Saitama is stronger than goku in latest mangga Saitama is limitless! he will never reach his maximum power because he does not have a maximum he is limitless, he will just keep increasing his power infinitely.
Secondly, some people claim that the writer of OPM(One) has said that the limit of Saitama's power is that he can destroy half a universe with one full-powered punch. This isn't true. One has never said anything like that, and it is only a rumor.
