While Deadpool is virtually unkillable due to his healing factor, he is not invincible. In fact, he's been beaten, maimed, and dismembered countless times in the comics and movies. Deadpool's immortality only extends to his ability to regenerate from almost any injury.
Deadpool is effectively immortal, although he has died several times. He is still alive 800 years in the future when the new X-Force encounters him. In addition, Thanos once declared that Deadpool should "consider yourself cursed ... with life!" out of jealousy over Deadpool's status as Death's love interest.
Deadpool also loves Death, so Thanos decided to curse Deadpool so that he will never die to keep the two apart. This helps explain why Deadpool's immortality is so much better than other characters with similar powers.
Everyone knows about the superheroes Deadpool has beaten, many of whom were courtesy of Deadpool's killing spree against the Marvel Universe. However, this is not one-sided. Just because he has a healing factor doesn't mean he can't lose; it simply means his opponent has to get creative to find a way to keep him down.
Deadpool's immortality lies in his cancer and regeneration ability. According to the comics, cancer triggered his healing powers. As a result, the cancerous cells regenerate just like the normal, healthy ones do.
Deadpool is easily one of the most powerful characters Marvel has. The fast-talking gunman seems almost fearless on the battlefield, but in reality, there's a lot that scares the Merc with the Mouth. There are two things though, that scare him above all: cows and clowns are a Deadpool weakness.
Deadpool's Face & Skin Don't Heal Because Of His Cancer
Similarly to his Marvel Comics counterpart, Wade Wilson was diagnosed with terminal cancer in 2016's Deadpool, which spurred him to undergo experimentation in an effort to unlock his latent mutant abilities and cure his cancer.
He is somewhat the same in the comics, so if Deadpool ever faced Thor, the god of thunder would have the winning edge. It's true that Deadpool managed to terminate Thor using Pym Particles in a non-canon comic by enlarging Mjolnir. But MCU Thor never needed Mjolnir in the first place.
Fans have already seen the outcome of the clash when the superheroes first collided in 2009's X-Men Origins: Wolverine. On that occasion, Wolverine proved he was stronger than Deadpool, who still went as Weapon XI at the time.
While Thor is powerful and his strength is said to be unmatched, he is not strictly immortal like other mythological gods. He is susceptible both to aging and to being killed in battle. Like other Norse gods, he must consume special apples kept by the goddess Idun to keep from aging.
He was welcomed by the X-Men as a member and has a connection to them, to the point he considers them his family. His deeds are admired by many heroes, some villains, and also by the average man. Wolverine is a killer, but one who managed to become a hero. Deadpool is not, he knows it and he hates it.
Months later, T-Ray, now an agent of Thanos resurrects Deadpool, who has been killed in a fight with Weapon X, using an artifact Thanos gave him to create many copies of Deadpool. Thanos is jealous of Deadpool's relationship with Death and T-Ray is to "curse him with immortality" so that he may never see Death again.
Powers. Extended Lifespan - It is unknown how long Deadpool will live but it has been shown to be further than 800 years into the future, it is believed he is unable to die as he has established a romantic like relationship with the personification of Death.
Deadpool can survive a nuclear bomb -- how hard could it be, right? The merc has been known for being indestructible, but you would have never guessed that he could survive his very atoms being blown to bits.
Wolvie and Deadpool neither die nor can get older if they retains own healing factor. Hence they both ARE immortal. But yes they will die if get killed and cut into small pieces. How did Deadpool kill each of the individual characters in the Deadpool Kills the Marvel Universe series?
He becomes infatuated with Death after having a number of near-death experiences. During the Funeral for a Freak storyline, Death appears to reciprocate the feeling, and a jealous Thanos prevents Deadpool from dying and joining the entity by cursing him with immortality.
Deadpool never has killed Ghost Rider. A Version of Deapool has killed a version of Ghost Rider atleast twice tho. This is seemingly accomplished by decapitating a ghost rider using his own chain. A Deadpool somehow kills a ghost rider again.
Goku is always on guard in this form and would easily destroy Deadpool with a simple ki wave. Goku and the other Z-Fighters have already fought beings capable of regenerating their entire bodies, so Deadpool is no different.
In the end, Deadpool wasn't worthy. While he seemingly had control of Mjolnir and the strength of Thor, it was all a mirage put on by Loki to distract Thor. It's a shame because Deadpool looked pretty cool with the enchanted hammer. But, it makes sense that Wade Wilson - of all people - isn't worthy.
As powerful as Cosmic Ghost Rider is, Immortal Hulk would destroy him. Castle couldn't do anything that would actually kill him, which would give Immortal Hulk time to destroy his foe.
Ultimately, the Merc with the Mouth became a fan-favorite hero, and in modern stories, his healing outshines even that of Wolverine, with Wade able to survive incredible injury, from decapitation to incineration.
Vanessa Carlysle, also known as Copycat, is one of the most well-known love interests Deadpool's had. This is thanks to Vanessa being the primary love interest in the hit films starring the Merc with a Mouth. However, the movies don't reveal that she's a shapeshifter and depict her instead as a normal human.
Deadpool may be able to regenerate but no matter how many times he gets back up or reattaches his head, the Hulk will always smash him back down. During the animated movie Hulk vs Wolverine, we get a fairly accurate representation of what this might look like.
