Muramasa Blade: Wolverine's only specific vulnerability known to date. Created by having his soul infused into the katana, the efficiency of his mutant healing factor is decreased dramatically if he sustains injury from the Muramasa Blade.
Meanwhile, the Adamantium was constantly poisoning his insides; Logan's healing factor initially kept the metal's toxicity in check but, as it gradually failed, the poison began overwhelming his system and killing him. Adamantium poisoning may also have turned into the cause of his healing factor's increasing failure.
While Wolverine's powers have allowed him to survive having his skin and muscles burned away by the villain Nitro, it takes a significant amount of time for Logan to regenerate the biological material lost to injury, and it's generally understood that if his bone marrow (the source of his healing) is burned away, he ...
While he's best known for his adamantium claws, his strongest power is his healing factor. While it usually helps him recover from flesh wounds and the occasional brutal physical battle, Logan's most impressive feat with his healing factor was regenerating an entirely new body from a single drop of blood.
It depends on the writer as far as the organics. If they severed a limb at a joint, the adamantium won't grow back - except the Krakoa 5 can add it back.
However, they are not identical. Deadpool has the superior healing factor, significantly. Professor X once stated that Wolverine could, most likely, be killed if he was decapitated. Deadpool can still move his body around normally even with a decapitated head.
Despite getting cut in half and shot to bits, Wolverine managed to make it out of the violent situation alive. However, he still felt the pain and he'll have to deal with the mental trauma that comes with it.
The Hulk has one of the most powerful healing factors in the Marvel Universe, but his regenerative powers have an incredibly dangerous flaw. Most other characters with healing factors like Wolverine and Deadpool will always heal back in the same way, as their bodies rapidly repair damage.
In Marvel Comics, adamantium and vibranium weapons have gone toe-to-toe on several occasions, and the former usually comes out on top. However, in Marvel's live-action projects in the MCU and Fox's X-Men Universe, vibranium is clearly the stronger substance, and the more versatile.
Sabretooth generally is superior to Wolverine in every single way and regard, including healing. Logan has fought Creed on multiple occasions and hasn't been able to cut through him, since Sabretooth has the better healing and his Adamantium bones don't deal with the same Adamantium poisoning making i…
Weaknesses. Muramasa Blade: Wolverine's only specific vulnerability known to date. Created by having his soul infused into the katana, the efficiency of his mutant healing factor is decreased dramatically if he sustains injury from the Muramasa Blade.
In X-Men #25 (1993), Magneto rips the adamantium out of Wolverine's body. This screws up his healing factor, and they reveal in the story that his claws are actually bone. The bone claws have the ability to grow back when broken.
In The Wolverine (2013), Wolverine loses his Adamantium claws, and he regains them in X-Men: Days of Future Past. The original Weapon X storyline revealed the origins of Wolverine's claws and explored more character development for him.
While the version of the character in Earth 616 (the mainline Marvel universe) cannot resurrect from a single cell (unlike the Ultimate Marvel variant), Wolverine can regrow giant wounds and entire limbs easily.
Deadpool is effectively immortal, although he has died several times. He is still alive 800 years in the future when the new X-Force encounters him. In addition, Thanos once declared that Deadpool should "consider yourself cursed ... with life!" out of jealousy over Deadpool's status as Death's love interest.
His adamantium claws are one of the few weapons in the Marvel Universe that can consistently pierce Hulk's skin and Wolverine has no problem going for Hulk's head. In fact, if it came down to it, Wolverine could cut Hulk's head off, ending the Hulk once and for all.
In multiple comics over the years, it's been established that Deadpool's healing factor is more powerful than Wolverine's. Deadpool can survive anything. If his head is cut off, he'll regrow his body over a few weeks. He can heal almost instantly from pretty much any wound.
Marvel has confirmed that Sabretooth's healing factor is stronger than Wolverine's. The two mutants have long been adversaries, their respective healing factors allowing them to survive for many years to continue their fight.
Deadpool: After receiving his healing factor from Wolverine's DNA, Wade also gained the ability of a longer lifespan. He then became practically immortal due to Thanos placing a curse on him so he could never be with the love of his life Death.
However, for some reason, Wolverine has never been able to defeat Juggernaut on his own. That doesn't mean he wouldn't try. Wolverine even tried to fight Juggernaut when all he had was bone claws. However, Wolverine has never been able to beat this unstoppable foe.
The key in all these cases seems to be circumventing Wolverine's regenerative abilities by killing him so completely that there's nothing left to regenerate. He also survives a lot of other terrible things, too. When he's going to starve to death he eats his own body.
Summary. The first thing Wolverine's Adamantium claws couldn't cut through was the Hulk's skin, as seen on the third page of Wolverine's comic book debut in Incredible Hulk #181.
