Goku has a complete fighting style while Superman doesn't and can sense where superman will be but superman can counter with mind reading. Goku's battle sense is equal to superman's intellegence.
In-universe, Suppaman is Dragon Ball's Superman, and it's been confirmed that he can't even match the likes of General Blue. This means that Goku is far stronger than his universe's 'Superman', proving once and for all that Goku is superior within the confines of Dragon Ball continuity.
He's not intelligent, but more wise. Like a sage, he knows more morally and spiritually, but he's no slouch when it comes to actual intelligence, he just doesn't quite match Superman's intellect.
Even if Goku was able to use his highest form of power, Saitama's one-punch certainty means a fight wouldn't last for long. If we are to take Saitama's power and accuracy at face value, it almost doesn't matter who his opponent is — he would win outright.
Beerus, the God of Destruction in charge of Universe 7, is amongst the strongest gods of all. Beerus' powers is so immense, his punches can make the entire universe shake. Superman would have a hard time trying to land a good punch against such a being.
If Superman cannot survive the erasure of his own universe, what chance does he stand against Zeno's Erase ability? Considering that Superman cannot hurt Zeno nor survive his single technique, Zeno would absolutely defeat Superman, even at his strongest.
Superman doesn't like fighting, but he knows how to end battles against powerful foes quickly. Goku is at a disadvantage against Superman for a lot of reasons. Once Superman knows what he's dealing with, he'll cut loose and take Goku down.
Although Naruto's physical strength isn't on the level of Goku's, he can certainly do well against him in a fight. With Naruto's limitless chakra and other such overpowered abilities at his disposal, like the Six Paths Sage Mode, Naruto would be able to hold his own, at least for a while.
Beerus, no question. Saitama's best feats (getting kicked to the moon and jumping back to earth, splitting a life wiping energy beam, destroying a giant meteor etc) would barely place him at Namek Saga levels by DB standards.
Vegeta is far stronger than Saitama. I mean just look at Vegeta. When he had a power level of mere 18000 in the saiyan saga, he was able to destroy the alien planet Arlia with absolute ease.
Thor is currently more powerful than Goku. If it was base Thor, then things would be close between him and Goku. However, Thor became the All-Father, which granted him the Odin Force.
Goku is definitely stronger at a base level, but Hulks are known for their ability to take immeasurable amounts of damage. Red Hulk is no different, with his invulnerability and healing factor allowing him to survive basically anything.
Even Goku, at his most powerful, is unlikely to be able to even lay a finger on him, but frankly, that applies to anyone who would try to go one-on-one with Thanos when he has the completed Infinity Gauntlet.
While Superman could potentially overpower Thor, blows rendered by the mystical Mjolnir would likely impose serious damage on the Kryptonian hero. With his super-speed, the Man of Steel could probably avoid the Thunder God's lightning, but not necessarily, since Thor is just as fast.
As such, if Batman were to triumph against an opponent such as Goku, he'd have to rely on his wits to win the day. An oft-repeated phrase for Batman fans is that he can beat anyone "with prep time" and it's likely that the Dark Knight's best chance against Goku would involve a lot of preparation and observation.
While Goku would likely have Mario face him at his strongest, Mario at his max strength still wouldn't be enough to overpower Goku in a drawn-out fight.
Wiz: In their base forms, Beerus triumphs Thanos. Thanos doesn't have enough firepower to put Beerus down for good. Thanos might be known to destroy planets and solar systems with effort, Beerus can destroy solar systems with ease.
As Dragon Ball Ki operates the same for defense as it does offense, then Krillin's signature technique would let him deal a fatal blow to Saitama, who has yet to show power or durability on that level. And anyways, the Destructo Disk's whole selling point is how it can harm opponents far above Krillin himself.
Not by any chance. Goku is one of the most powerful anime character and Kakashi is not even in top 50 powerful characters. The only advantage Kakashi have is more intelligence than Goku. But it will not matter if he's going against an anime God.
In the eyes of many shonen fans, One-Punch Man's Saitama is the sole anime character that stands a chance against Goku in one-on-one combat. The baldheaded hero takes out world-level threats without breaking a sweat, making him a prime candidate to unseat Goku as the anime medium's strongest fighter.
Itachi would probably lose to Goku in strict hand-to-hand combat, although he could hold his own for a while, but Itachi's true strength lies in his non-physical capabilities.
After going through the transformation, Goku became one of the strongest— if not the strongest— mortal beings in the Dragon Ball Multiverse. If someone from the Marvel Comics wants to take him on, then they need to be cosmic beings or Gods, basically.
Superman emits an aura but it doesn't even get discharged up to a centimeter form his body. So in strength, Goku would win, the reason being, he's defeated enemies physically stronger than him countlessly.
When necessary, Goku has been faster than The Flash, but it's the source of The Flash's powers, and his years spent mastering the way he and his enemies respond to speed, that holds his best weapon.
