Only a few select people can withstand his seemingly endless talking, and his mouth is sewn shut in the final act of X-Men Origins: Wolverine. Ajax also threatens to sew Wade's mouth shut in Deadpool when he is undergoing his cancer treatment because of his nonstop talking.
Given Deadpool's established need to speak incessantly despite the situation, he would have unleashed a swarm of locusts he'd be unable to control. However, with his mouth sewn shut, Deadpool can better regulate the disgusting ability.
Despite being able to heal from the gravest wounds, Deadpool is unable to heal the scarring on his face and body in his recent film appearances. Ryan Reynolds debuted as Wade Wilson in 2009's X-Men Origins: Wolverine before rebooting the character in his signature comedic style in 2016's Deadpool.
Why doesn't Deadpool have the powers he had in Wolverine?
However, the cells Wolverine's healing factor attached itself to within Deadpool's body were cancerous. That means whenever Wade suffers an injury, Deadpool's body replaces those dead cells with dying cells, which - themselves - are perpetually being replaced by other dying cells in an unending cycle.
These "super-cancer" cells persistently destroy his healthy cells while his healing abilities rapidly regenerate them. This endless conflict between the healing factor and the cancer cells results in Wilson's disfigured appearance. His inability to heal his skin lies in his failure to cure his cancer.
It has been revealed that at the time his healing ability was given to him, Deadpool suffered from some form of cancer; after the healing factor was given to him, it made his normal cells as well as his cancerous cells unable to die, giving him a heavily scarred appearance beneath his suit.
However, they are not identical. Deadpool has the superior healing factor, significantly. Professor X once stated that Wolverine could, most likely, be killed if he was decapitated. Deadpool can still move his body around normally even with a decapitated head.
Most likely, Deadpool would have to place his head back onto his neck, and it will then Regenerate in that location. This is also seen possible because of this, yes I know this is just epic cover art to build suspense, but it shows us that Deadpool can actively hold his head rather than it just regenerating instantly.
Determining who is stronger between Deadpool and Wolverine is subjective, with Wolverine being more accomplished and experienced, while Deadpool has an edge in skill, unpredictability, and healing factor. The outcome of a fight between them in Deadpool 3 would likely favor Wolverine.
His power is so effective that it allows him to be immortal despite him carrying his cancer. But that doesn't mean he is unkillable. One way of killing him is to put a mutation-dampening collar on his neck. It will disable his regenerative ability and allow the cancer cells to grow, thus deteriorating his body.
Yes, Deadpool feels every bit of pain as normal humans do. However, his regenerative ability allows him to heal from all injuries. While Deadpool can heal quickly, he isn't indestructible.
In Deadpool (2016), set in a revised timeline created by the X-Men. This version is a mercenary who is diagnosed with late-stage cancer and turns to Weapon X after he is offered a cure.
While Wade does get inebriated if he drinks a lot of alcohol, his body's super-powerful immune system protects him from getting drunk easily, meaning that Wilson needs a lot of alcohol in his system before he can even remotely be affected.
It's when Wade Wilson aka Deadpool (Ryan Reynolds) is stuck on the couch of his elderly blind roommate Blind Al (Leslie Uggams) while his legs re-generate, having been earlier torn in half by Juggernaut (oh yeah, that was pretty crazy, too). We first see the stumpy legs – and possibly more – as Wilson sits.
There's a reason for that. The Merc with the Mouth has an advanced healing factor derived from Wolverine's powers, but that's where those similarities end. When William Stryker pooled a bunch of mutants' powers into Wade Wilson in X-Men Origins: Wolverine, he went ahead and gave Deadpool an adamantium skeleton.
He's split straight down the middle, but he had been melded together with Madcap for the duration of the issue, so the two halves simply become each of them. Since there was no technical injury, the two guys come out unscathed and fully formed.
While most people have a hard time resisting the cuteness of kittens, Deadpool notoriously mentioned that the young furry felines are his one true weakness.
Another piece of information that is interesting to consider, is Joe Kelley's Spider-Man/Deadpool run. There it is established that the reason for Deadpool not regenerating is purely psychological, his low self-esteem is what stops him from returning to his normal appearance.
Readers witnessed Wade Wilson's rapid regeneration abilities and Rogue's absorption powers work together at an unbelievable level, saving Rogue's life – and proving Deadpool can survive a nuclear blast.
Deadpool might have his fair share of comedic moments in the Marvel universe, but the mercenary's powers allow him to be one of the strongest Marvel characters, proficient enough to defeat and kill major Marvel heroes ranging from Captain America to The Fantastic Four.
Extended Lifespan - It is unknown how long Deadpool will live but it has been shown to be further than 800 years into the future, it is believed he is unable to die as he has established a romantic like relationship with the personification of Death.
In multiple comics over the years, it's been established that Deadpool's healing factor is more powerful than Wolverine's. Deadpool can survive anything. If his head is cut off, he'll regrow his body over a few weeks.
Peter Parker always cracks jokes and tries to find levity in serious situations. Spider-Man's attitude has rubbed Wolverine the wrong way for multiple reasons, and in one hilarious story, his hatred for Spider-Man was proven in a hilarious manner.
