Only five villains, namely Electro, Sandman, Vulture, Mysterio, and Kraven the Hunter responded to Doctor Octopus' request, and together they formed the Sinister Six (a name Mysterio came up with, according to Spider-Man).
Originally gathered by Doctor Octopus, the Sinister Six are a team of Super Villains who all have one persistent foe in common, the slippery wall-crawler known as Spider-Man.
While Doctor Octopus has generally remained its leader, the Sinister Six has had multiple variations of composition. The original Sinister Six–Kraven the Hunter, Mysterio, Doctor Octopus, Vulture, Sandman, and Electro–battling Spider-Man.
However, when Peter ran away to change into his Spider-Man costume, a zombie version of Spider-Man, who was transported to their world, took his place and battled the Sinister Six. Spider-Man then proceeded to kill and zombify them.
As envisioned in the comic books, Madame Web is not a villain. Instead, she's a hero who fittingly aids Spider-Man using her clairvoyant abilities. In the comics, Madame Web's real name is Cassandra Webb, and her psychic powers are due to her being a mutant like the X-Men.
A mercenary for hire, he played an important role in the series Deadpool; T-Ray served to remind Wade Wilson, also known as Deadpool, what a failure he was. He is Deadpool's archenemy for many issues and almost everything that happened to Deadpool was a part of an elaborate plan orchestrated by him.
By far the most brutal death is when Deadpool kills Spider-Man while wearing the Venom symbiote. Deadpool uses the symbiote's ability to bypass Peter's spider-sense in order to ambush him. He then quickly overpowers Spider-Man, and horrifyingly, eats his brain while Peter is completely helpless to stop him.
Loki – Thor's archenemy and adoptive brother. The son of Laufey, ruler of the Frost Giants of Jotunheim, one of the "Nine Worlds" of the Asgardian cosmology. He is a master of spellcasting and trickery.
In the first Spider-Man animated series, the Kingpin formed a version of the Sinister Six. In the animated series, this version was called the Insidious Six. However, in the comics, the Kingpin hasn't had any involvement with the Sinister Six.
The Sinister Six is a group of Spider-Man villains seeking revenge on the hero, with each member having a grudge against him. There are several potential villains in the DC universe who could form a similar team against Batman, such as Poison Ivy, Mr. Freeze, and The Penguin.
Other mainstays such as Vulture and Electro, along with new versions of Mysterio and Kraven the Hunter, took part in this hunt for Doctor Octopus. During a fight with Spider-Man, the Sandman's new team gained their sixth member: Venom.
The more likely option is that it will be connected to Sony's new universe of Spider-Man characters, taking part in the same universe as Venom and Morbius. Either way, No Way Home didn't need the Sinister Six in the end, and it has kept the door open for Sony, or even Sony and the MCU, to use them in the future.
As you all know, Wolverine kills Deadpool at the end of X-Men Origins:Wolverine, but somehow Deadpool returns around 30 or so years in the movie timeline later for 2 more solo movies and another one upcoming.
Mjølnir: Thor was wielding the magical Uru hammer, which he had lost when he was banished from Asgard. However, before Thor could retrieve the Mjølnir from S.H.I.E.L.D., he was killed by Hawkeye.
Crossbones snipes at him while he was walking Sharon Carter (Agent 13; Cap's girlfriend), who has been brainwashed by Doctor Faustus, posing as a S.H.I.E.L.D. psychiatrist, delivers the killing shot. Overwhelmed with guilt, S.H.I.E.L.D. director Tony Stark and Black Widow hunt Captain America's murderers.
The Leader (Samuel Sterns) is a supervillain appearing in American comic books published by Marvel Comics. The Leader first appeared in Tales to Astonish #62 (December 1964), created by writer Stan Lee and artist Steve Ditko as the archenemy of the Hulk.
Diamondback (Willis Stryker) is a fictional character appearing in American comic books published by Marvel Comics. He is primarily an enemy of Luke Cage and is notable for being the first major supervillain that he faced. Stryker/Diamondback in Heroes for Hire #1. Art by George Tuska.
Kingpin - A ruthless crime lord and the archenemy of Daredevil, indeed uncontested as Daredevil's greatest enemy. The Kingpin also serves as an enemy for the Punisher and Spider-Man.
Dr. Michael Morbius, Ph. D., M.D., better known as simply Morbius, is an anti-heroic antagonist from Marvel Comics, serving as an enemy to Spider-Man, Blade, and Ghost Rider. He was a biogenetic scientist who was dying of a blood-destroying disease.
Ezekiel Sims' biggest trait is his selfishness. As he himself notes, Ezekiel scoffs at the idea of helping others, willing to kill and ruin the people around him for his own self-benefit as he reasons that the only person in his life that ever matters is just himself and himself alone.
Who is the main villain in Spider-Man Across the Universe?
Jason Schwartzman as Johnathon Ohnn / the Spot: A former scientist from Alchemax-turned-supervillain after an accident, whose body is now covered by interdimensional portals that allow him to travel through space and different universes.
